Search results for "Gastrointestinal mucosa"
showing 3 items of 3 documents
Bioavailability of Glucosinolates and Their Breakdown Products: Impact of Processing.
2016
International audience; Glucosinolates are a large group of plant secondary metabolites with nutritional effects, and are mainly found in cruciferous plants. After ingestion, glucosinolates could be partially absorbed in their intact form through the gastrointestinal mucosa. However, the largest fraction is metabolized in the gut lumen. When cruciferous are consumed without processing, myrosinase enzyme present in these plants hydrolyzes the glucosinolates in the proximal part of the gastrointestinal tract to various metabolites, such as isothiocyanates, nitriles, oxazolidine-2-thiones, and indole-3-carbinols. When cruciferous are cooked before consumption, myrosinase is inactivated and glu…
Advances in confocal laser endomicroscopy for the diagnosis of gastrointestinal diseases
2009
Confocal laser endomicroscopy (CLE) is a novel technique enabling in vivo microscopy of the human gastrointestinal mucosa. Cellular details even below the tissue surface can be visualized at high resolution during ongoing endoscopy.This review summarizes the current clinical data on the use of CLE in different disease states and discusses a perspective for future clinical and scientific application of CLE.Review on published literature and meeting abstracts.Confocal laser endomicroscopy covers a growing field of indications in both upper and lower gastrointestinal endoscopy and beyond. It has been shown to reliably predict the presence of neoplastic lesions and inflammatory changes of the g…
The renin–angiotensin system in gastrointestinal functions
2023
In this chapter, we describe the role played by classical and alternative renin–angiotensin system (RAS) in the physiological regulation of gastrointestinal functions. RAS modulates gut motility and mucosal functions, including secretion, fluid, and nutrient absorption. We focus mainly on the activation of angiotensin II type 1 and 2 receptors located on the smooth muscle and epithelial cells or on the enteric neurons. Few studies indicate that alternative RAS may counteract classical RAS functions. Although data on the enteric RAS system are still scarce, they encourage further investigations in consideration also of a potential involvement in gastrointestinal disorders.